Fever, nephrotic syndrome, and rapidly progressive renal failure
نویسندگان
چکیده
منابع مشابه
Clinical approach to rapidly progressive renal failure.
Rapidly progressive renal failure (RPRF) is an initial clinical diagnosis in patients who present with progressive renal impairment of short duration. The underlying etiology may be a primary renal disease or a systemic disorder. Important differential diagnoses include vasculitis (systemic or renal-limited), systemic lupus erythematosus, multiple myeloma, thrombotic microangiopathy and acute i...
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Sir, In their article in Nephrology Dialysis Transplantation w1x, discussing the pathophysiology of acute renal failure in the nephrotic syndrome, Koomans et al. (p. 223) mention that obliteration of epithelial slit pores, as visualized by electron microscopy, is not correlated with the reduction in glomer-ular ®ltration rate (GFR) in humans. However, in a previous
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Four patients with idiopathic membranous glomerulonephritis, heavy proteinuria and progressive renal failure received azathioprine and prednisolone. Renal function improved in all four and proteinuria declined sharply in three. We suggest that treatment with azathioprine and prednisolone may be of benefit in this form of idiopathic membranous glomerulonephritis.
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Reply Sir, We thank Drs Calo and Davis for highlighting their interesting studies. We were, in fact, aware of these studies and have used them as background in grant applications in the broader context. Our paper was not intended to be a review of the literature, since this area, we believe, is still evolving. It is always a subjective decision which references to include or not in any given pu...
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ژورنال
عنوان ژورنال: Kidney International
سال: 2007
ISSN: 0085-2538
DOI: 10.1038/sj.ki.5002298